Which version of Excel do you have? I think it might be that the modern "Ribbon" interface isn't a menu in the same sense that GuiTest expects. Using the advice that Corion and marto gave, I was able to use SendKeys('%FS') to perform a save, but not the MenuSelect with either '&File|&Save' or 'File|Save'.

Also, regarding FindWindowLike(), I was able to match windows with 'Excel' and 'Book1', but not with the patterns including the hyphen:

use strict;
use warnings;
use Win32::GuiTest qw(:ALL);

foreach my $like ( 'Excel', 'Book1 - Excel', 'Book1.xslx - Excel', 'Bo
+ok1') {
    my @window = FindWindowLike(undef, $like);
    unless (@window) {
        warn "Couldn't find '$like'\n";
        next;
    }
    print $like, @window;
    foreach (@window) {
        SetForegroundWindow( $_ );
        SendKeys(join '{TAB}', "Hello World", $like, $_, GetWindowText
+($_), "{ENTER}");
        #MenuSelect("&File|&Save");
        #MenuSelect("File|Save");
        SendKeys('%FS');
    }
}
__END__

__OUTPUT__
Excel    1903500    6817874    1580572
Couldn't find 'Book1 - Excel'
Couldn't find 'Book1.xslx - Excel'
Book1    1903500    4919696
[download]