Although there are perl tools to read directly from your input file: Spreadsheet::XLSX (it comes with an example that will get you up and running in no time, just remember to do "cpanm Spreadsheet::XLSX" to install the extra libraries), I think it is better to save the spreadsheet as csv and read it in with something like Text::CSV.

you can implement it in pure perl, or mix a bit of .bat code, to bring up a notepad with your results.

As for something that types in the results, and alt-tabs to excel and notepad individually, try another language, specialized in Windows, for example Autoit3, and that has a working multiping example.

However, if you want an automated, lightweight, app that runs each 10 minutes, and report if thresholds are out of range... do it in Perl. :)

There are some perl GUI's... but it is not for beginners.

so for example: