Either I’m a liar or you’re a moron. Nah, I’m just kidding. You’re okay!

A recapitulation of part of my setup, simplified and tested. The link I gave already has all this information and more. You have to have uWSGI with the PSGI extension built, as already mentioned–

> emacs /opt/app.psgi
#!/usr/bin/env perl
sub { [ 200, ["Content-type" => "text/plain"], ["OHAI"] ] }
--
# Start the apps.
> /opt/uwsgi_latest_from_installer/uwsgi --uid moo \
  --pidfile /tmp/one.pid --socket 127.0.0.1:8100 \
  --psgi /opt/app.psgi --processes 1 --master \
  --daemonize /tmp/one.log

> /opt/uwsgi_latest_from_installer/uwsgi --uid moo \
  --pidfile /tmp/two.pid --socket 127.0.0.1:8200 \
  --psgi /opt/app.psgi --processes 1 --master \
  --daemonize /tmp/two.log
--
# Edit the nginx config by adding the endpoints.
> emacs /etc/nginx/sites-enabled/your-site-config.conf
--
  location /one {
     include uwsgi_params;
     uwsgi_pass 127.0.0.1:8100;
     uwsgi_modifier1 5;
  }
  location /two {
     include uwsgi_params;
     uwsgi_pass 127.0.0.1:8200;
     uwsgi_modifier1 5;
  }

# Restart nginx and visit
# http://yourdomain/one
# http://yourdomain/two
[download]