> I've spent some time looking into these two methods for removing appenders but it turns out that you can only use them if you manually create the appenders (with Log::Log4perl::Appender->new) and add them (with $log->add_appender).
You can still access all the appenders with the Log::Log4perl class method appenders(), which returns a HASHREF to all the appenders that currently exist:
Log::Log4perl->appenders()->{'Screen'}->threshold($OFF);
will disable logging to the screen appender.