Aha, ok, I see, probably I just ran into the exact ones by chance...
I know I am pushing my luck a bit, but since you have been so helpful and the code is yours, is there a way that I can see which of the 10-mers are consecutive and "paste" them into one larger match?
AGCAATATTTCAAG
AGCAATATTTCAAG
GCAATATTTCAAGA
GCAATATTTCAAGA
For example, these 2 are basically the same, just going 1 position further.
Hm, now that I am thinking it better, was the problem I asked for a question of finding the longest possible match with one mismatch allowed? Would that have been easier and I was wasting everyone's time here? | [reply]
[d/l] |
> is there a way that I can see which of the 10-mers are consecutive and "paste" them into one larger match?
It's not so easy. You can't paste them together, as that might increase the number of mismatches over the threshold.
But you can change the algorithm totally if you want to find the longest matches. Just move the shorter string alongside the longer one, and then for each position try to find the longest match starting there.
#!/usr/bin/perl
use warnings;
use strict;
use feature qw{ say };
my $stretch = 10;
my $mismatches = 1;
substr $reference_str, 0, 0, 'x' x (length($small_str) - 1);
$reference_str .= 'x' x (length($small_str) - 1);
for my $start_pos (0 .. length($reference_str) - length($small_str)) {
my $substr = substr $reference_str, $start_pos, length($small_str)
+;
my ($from, $diffs) = (0, 0);
for my $inner_pos (0 .. length($small_str) ) {
++$diffs if substr($substr, $inner_pos, 1)
ne substr $small_str, $inner_pos, 1;
if ($diffs > $mismatches || $inner_pos == length($small_str) )
+ {
say join "\n\t",
$start_pos + $from + 1 - length $small_str,
substr($small_str, $from, $inner_pos - $from),
substr($reference_str, $from + $start_pos, $inner_pos
+- $from)
if $inner_pos - $from >= $stretch;
++$from until (substr $small_str, $from, 1) ne substr($sub
+str, $from, 1) || $from > $inner_pos;
++$from;
--$diffs;
}
}
}
> was the problem I asked for a question of finding the longest possible match with one mismatch allowed?
Basically, yes.
($q=q:Sq=~/;[c](.)(.)/;chr(-||-|5+lengthSq)`"S|oS2"`map{chr |+ord
}map{substrSq`S_+|`|}3E|-|`7**2-3:)=~y+S|`+$1,++print+eval$q,q,a,
| [reply]
[d/l]
[select] |
I think it does what I needed!
I will now study the code you kindly provided, thank you very much!
| [reply] |