Not sure about a Perl-oriented one, if such a beast exists, but for a general guide I tend to use the almost-standard 'Design Patterns' by Gamma, Helm, Johnson, and Vlissides. Examples in this are in Smalltalk and C++, and some patterns don't map too well onto the Perl brainspace. Admittedly you do end up spending a lot of time looking at the examples and going 'Now what would I use this for myself..?", but I find this with many architectural/design books.

The only Perl-specific Design Patterns resource I've yet seen is the heavily incomplete webpage at http://www.patternsinperl.com. Some nice discussions on a few patterns, but not too much as yet.