I've tried both PDK (PerlApp) from ActiveState and Perl2Exe from IndigoStar. Here are a few of the things I've found:

Perl2Exe compiles code for more platforms than PerlApp.
Programs compiled with Perl2Exe have smaller file sizes than those compiled with PerlApp.
Programs compiled with Perl2Exe have smaller memory foot prints than those compiled with PerlApp.
Programs compiled with PerlApp tend to load in memory faster than those compiled with Perl2Exe.
Programs compiled with Perl2Exe garbage collect faster than those compiled with PerlApp.
Neither product has very good tech support (I've received more help here than at either site).
Perl2Exe is less expensive than PerlApp.

One thing to keep in mind is that I evaluated the products before I purchased. Both products say they do not require purchase before running at production quality. I took this to mean that the products would not get better upon purchase. My final decision was Perl2Exe. I have never had trouble with Perl2Exe not getting a library to compile (and be portable).

This is just my experience. Others may have experienced different.