Yes, you can. It's not portable though, so be aware.
It isn't trivial either, and there isn't any specific Perl
support for it. Under System V Release 4, you would use a
stream pipe and ioctl. On BSD, you would use a Unix Domain
Socket.
Details, including example code (in C), are to be found in
Stevens' Advanced Programming in the UNIX Environment
in the chapter Advanced Interprocess Communication.