Do you want spaces or whitespace? You use \s, but you say replace 2 spaces. Here is how you could replace two spaces (not tabs or newlines) and all double quotes:

use strict;

my %replace = (
   '"'  => '',
   '  ' => ';',
);

s/("|  )/$replace{$1}/g;
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jeffa

L-LL-L--L-LL-L--L-LL-L--
-R--R-RR-R--R-RR-R--R-RR
B--B--B--B--B--B--B--B--
H---H---H---H---H---H---
(the triplet paradiddle with high-hat)