I faced similar problems several years ago when did such type of programming, and that is why I suggested you to try perl/Tk and may be other GUI/C++ framework and perl embed into it. Beleive me, the deeper you go into Win32::GUI the more problem you will get!

At least you should not develop *serious* application with this module.
Otherwise something bad is going to happen! (okay, I'm joking)

Best wishes,
Courage, the Cowardly Dog.