I have to agree with Spudz. Perl::Tk is sweet for the GUI stuff. The only hassle is that you not only have to learn Tk, but how the Tcl interface is reimplemented in Perl. It's not an easy transition, I've found, and I really liked the "Learning Perl/Tk" book for that reason. Others didn't like the writing style, though, so buyer beware. For better or worse, though, it is the only one-stop-shop for learning about Perl/Tk.