How about dividing the problem into two regexes?

    while (<>) {
        chomp;
        next if (/(H|IF)-000$/ or !/^PH/);
        print "$_\n";
    }
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Second thought: I just noticed that your description and your regexes differ, so I'm not sure whether you want to match IF-000 or I-000. If you want the latter, use

        next if (/[HI]-000$/ or !/^PH/);
[download]

But I guess that's obvious.