My own approach was to use CGI::Application. The advantage I found was that a) support for HTML::Template is built-in, thus allowing me to use any template design I want. b) I can create a super-class that can auto-magically take care of session and user management each time one of my scripts runs. Basically it looks like this:

script.cgi:

use MySite::SubClass;

my $webapp = MySite::SubClass->new();
$webapp->run();
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MySite::SubClass:

package MySite::SubClass;

use MySite::SuperClass;

sub setup {
    # setup runmodes and script specific stuff
    # ...templates perhaps?
}

# …
# runmodes subs and whatnot :)
# …

1;
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MySite::SuperClass:

package MySite::SuperClass;

use base 'CGI::Application';
use CGI;
# other modules here..

sub cgiapp_init {
    my $self = shift;
    
    # create database handler
    # do session management
}

sub teardown {
    my $self = shift;
    
    # dbh->disconnect
}

# …
# other functions
# …

1;
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You can then create MySite::SubClass2 (etc…) which all use MySite::SuperClass and thus have session management taken care of.