There are no _inherent_ problems with chemically enhanced perception when coding. Course, the usual caveat applies of always review when ... ermm ... not chemically enhanced. It's the old thing about a new view on a problem. Like sleeping on it.
I tend to find my code and comments get distinctly silly when I do though, and so I _do_ have to go back and figure out how the heck I did that ... ;p
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It's not pessimism if there is a worse option, it's not paranoia when they are and it's not cynicism when you're right.