No, you cannot do that - The -M option cannot be used in shebang lines as it will generate an error. This option is intended for use only on the command line.

For example:

rob@kathmandu:~$ cat test.perl
#!/usr/bin/perl -Mstrict -Tw

print "foo!\n";
rob@kathmandu:~$ ./test.perl
Too late for "-Mstrict" option at ./test.perl line 1.
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