At this point, there are a number of mature application frameworks for Perl which you should consider using. Take a look at the list here. Most have been discussed on this site, so do a little searching.
Comment on Re: Developing a Suite of CGI applications
Good call, however depending on the motivation will depend on the path chosen. For example, i build my framework to extend my knowledge on design and abstraction in coding..
It's not as if there is no coding left to do when you use a framework. At best, it makes some of the boring repetitive parts go away and lets you work on the part that is specific to your application. One reason I recommend looking at these frameworks is that they are all open source and you can learn a lot about application design by looking at their code and seeing how they did it. I learned many things that way.