I don't believe you can do thing from a terminal based application. If you are using Win32::GUI, there maybe a way, but i dont think there is a way to capture MouseUp events (like VB), so you would have to partake of some XS hacking to add the feture (and i am sure people would thank you for it).

In Tk, you can use bind to do what you are thinking of (if i recall)

... take a look at the docs for these and other modules at the ever helpful search.cpan.org