Someone touched on it but did not go too far.

What about using WIn::OLE to connect to the ACCESS database.

Now if you are running the Unix box and your boss has the Win then one option would be to compile the perl script into a standalone script and drop it on your bosses system. Then when he wants to update the database, or you what to do it just log on and run the script.

MySQL <-> Perl <-> Win::OLE <-> ACCESS