I can only improve on what diotalevi said by pointing out that if one frame contains a document that contains a frameset, you can update multiple frames simultaneously by nesting them properly.

For example, if the main document looks like this:

<frameset>
  <frame src="A.html">
  <frame src="B.html">
</frameset>
[download]

And "B.html" contains:

<frameset>
  <frame src="B1.html">
  <frame src="B2.html">
</frameset>
[download]

Then you can reload B1 and B2 by reloading B.