in reply to stripping parentheses from only one line

If the URL is always the same, try this:
my $url = 'http://www.alwaysthesame.com'; s/"\($url\)"/"$url"/g; # match all occurences
If the URL could be anything, try this:
s|"\((http://[^)]+)\)"|"$1"|g;
If you post more details about your data and the problem you are trying to solve, I'm sure we can come up with a more helpful solution.