Perl/Tk is the most commonly used GUI API for Perl. It comes with a number of Perl installations by default (like ActiveState on windows). Here is a simple toy application that should give you some idea about how to code for it, but there are some other tutorials around, I'm sure.

Haven't used the wx interface so I can't tell you how that compares. I also don't run windows so I can't tell you about the icons.

Hope that helps.

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