Use require and put it in a BEGIN block. Don't forget to import any functions you might need. I'm not sure if that will catch a missing dll that is not loaded until it is used, but it will detect if the module you want to use is not installed.

#!/usr/bin/perl -w
use strict;
BEGIN {
    eval 'require NoneSuch';
    die "Hey, you forgot to install NoneSuch!\n\n" if $@;
    import NoneSuch ("ImportedFunc");
}
my $None = NoneSuch->new("foo");
ImportedFunc("bar");
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flounder