Depends on what you mean?

If you mean
pass an argument to 'perl' itself (eg. -d for debugger -v for version).
Then no (without some kind of wrapper) that would also be very dangerous.

If you mean
a command line argument for your script.
Then yes but you would want to use CGI. The CGI protocol is specifically built for passing arguments to a script through a hyperlink.
To specifially send arguments as command lines arguments read this . I have never tried this method, so I cannot attest to the safety.
IOW use at your own risk.
IOW you're better off using CGI.pm and coding as a CGI application.

I hope I'm answering your question. If not, please tell me what exactly you want to do.

grep

Mynd you, mønk bites Kan be pretti nasti...