I second the recommendation for LaTeX. The output is very professional. With pod2latex, you can easily pull in bits of a larger document directly from the perl modules which holds the original source of some material.

Coupled with the power of perl, you can easily pull in material from other sources (database, spreadsheets, variously formatted text files, etc.) and feed everything into a nicely formatted document that you can turn into great looking postscript or PDF document.