I can't tell you about PDF::API2, but I did use PDF::Labels and PDF::Create to output PDF files and they worked perfectly. The one thing I did discover is that I needed to turn off the print to fit option when printing the file as it sort of shrunk my page and the labels were not spacing properly.

If you're printing full pages that may or may not be a problem.

Good luck!

There is no emoticon for what I'm feeling now.