If you are a *NIX user or C programmer, don't worry about Perl. But worry about the Win32 troubleshooting with Perl-C, etc. Some things that can't be done or must be done differently. And some modules that seem that can't be adapted to Win32.

For the Win32 subject, best studied is ActiveState's distribution. They have a list of the failing modules & own a PPM system of installing them. They even simplified some bridges between Perl and ActiveX and provide a perlscript that would improve the old batch files, and some .asp programming with Perl, of course!