Your code seems good to me, all I can suggest is to try adding a few more arguments to you tie, as below. The code below is in use and works fine for me. More information would help, such as whether sessions are being stored and just not retreived. Are there any errors in the log files? Can you access any part of the session hash in your handler_request method?

HTH

    tie %{ $self }, 'Apache::Session::MySQL', $args{cid}, {
             DataSource     => 'dbi:mysql:database',
             UserName       => 'user',
             Password       => 'pass',
             LockDataSource => 'dbi:mysql:database',
             LockUserName   => 'user',
             LockPassword   => 'pass',
    };
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