You sure can.

At the very least, the following works from the command line (ActiveState 5.6.1 build 633)

You can put that system in a script, and store the directory in a variable. You must use (escaped) backslashes in the directory path, otherwise the explorer.exe program will be unhappy.

For more fine-grained control over the launching of the process you might want to look into the Win32 and Win32::Process modules.