in reply to Unix command line

You've got a few options. exec() will call the command and exit; system() will call the command and then return control to your program; and backticks and qx// will capture the output of the command.
my @who = `/usr/local/bin/who`;
It sounds like you want to use exec() or system(), though. Read perldoc -f system and perldoc -f exec for more info.