The following code will work PROVIDED there is always an entry in the FROM, DEPT, TO, ARR fields. It looks for the second pipe symbol, (|), and gets the rest of the line after it. Hope this helps.

Chris

#!/usr/bin/perl
use strict;
use warnings; 

while (<DATA>) {
    next unless /Bus Timetable/;
    <DATA> for 1..3;
    my $line;
    until (($line = <DATA>) =~ /^\+/) {
        
        # Find index of the first '|' after the first one.
        my $idx = index($line, "|", 1);
        
        # From that position (+2), capture the remaining string
        $line = substr($line, $idx+2);
        
        # Remove the '|' characters
        $line =~ s/\|//g;
        
        # Capture the first four fields
        my ($fr, $dep, $to, $arr) = split ' ', $line;
        
        print "$fr$dep:$to$arr\n";
    }
}

__DATA__

---TEXT BEFORE---


+---------------+
| Bus Timetable |
+---------------+----+------------+-----------+------+
| BUS SERVICE DAY tm | FROM  DEPT | TO    ARR | 24/7 |
+--------------------+------------+-----------+------+
| C4  metro   mon 15 | twn   0900 | Apt  1011 | yes  |
| C6  intl    mon 45 | LDN   1000 | XTR  1426 | no   |
| B2  susx    mon 20 | cly   1034 | btn  1118 | no   |
| A0  xxxxx   xxx xx | xxx   xxxx | xxx  xxxx | xxx  |
+--------------------+------------+-----------+------+


---TEXT AFTER---

+---------------+
| Bus Timetable |
+---------------+----+-----------------+------------+------+
| BUS SERVICE DAY tm | FROM  DEPT      | TO    ARR  | 24/7 |
+--------------------+-----------------+------------+------+
| C4          mon 15 | twn        0900 | Apt   1011 | yes  |
|     intl    mon    | LoDoN      1000 | XTR   1426 |      |
| B2  sussex      20 | cly        1034 | brgtn 1118 | no   |
| A0                 | manchester 1212 | xxx   xxxx | xxx  |
+--------------------+-----------------+------------+------+

****   RESULTS  *******
***********************

twn0900:Apt1011
LDN1000:XTR1426
cly1034:btn1118
xxxxxxx:xxxxxxx
twn0900:Apt1011
LoDoN1000:XTR1426
cly1034:brgtn1118
manchester1212:xxxxxxx
[download]