No. Well, not really, you can eval a block and use a storable module before and after to restore a chunk of them, but there is no real way to serialize and snapshot the vars globally. What are you trying to do? there may be a way to accomplish it in a differently.
I'm trying to debug a part of my script that comes after some very time-consuming operations. It takes a long time to sit through it all (about 20 minutes!) just to test one or two small changes, but I can't comment it out because the part I'm working on depends on the first part doing its thing.
Welp use Data::Dumper or Storable to write to a file the vars that are required for the second phase of the program after the fist phase quits. Then make a copy of the program pull out the long running phase and insert a section to load your variables before the second phase starts. That way you have the data structure of a real run stored and useable for debug without the long running portion running every time. The only limitations to this are if you are using coderefs or very complex structures.