Personally I use the ExtUtils::Embed option to generate the xs_init() code, and link that into my binary that includes perl functionality.

Parts of my Makefile look like this:

CONFIG_PM=-MConfig
PRIVLIB=`$(PERL) $(CONFIG_PM) -e 'print $$Config{privlibexp}'`
EXTUTILS_EMBED = $(PERL) -MExtUtils::Embed

PERL_CFG_CCFLAGS = `$(PERL) $(CONFIG_PM) -e 'print "$$Config{ccflags} 
+$$Config{cccdlflags}"'`
PERL_CFG_ARCHLIB = `$(PERL) $(CONFIG_PM) -e 'print $$Config{archlibexp
+}'`

PERL_CCFLAGS = -I$(PERL_CFG_ARCHLIB)/CORE $(PERL_CFG_CCFLAGS) $(PERL_H
+OOKS) $(TRACE)

STATIC_EXTS=Sybase::OpnSrv

XS_INIT = `$(EXTUTILS_EMBED) -e xsinit -- -std $(PERL_STATIC_EXTS) $(S
+TATIC_EXTS)`

CC=`$(PERL) $(CONFIG_PM) -e 'print $$Config{cc}'`
LD=`$(PERL) $(CONFIG_PM) -e 'print "$$Config{ld}\n"'`

....

SRC=xp_perl.c perlxsi.c ... # other files
OBJS=$(SRC:.c=.o)

perlxsi.c:
    $(XS_INIT)
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This generates a perlxsi.c file like this:

#include <EXTERN.h>
#include <perl.h>

EXTERN_C void xs_init (pTHXo);

EXTERN_C void boot_Sybase__OpnSrv (pTHXo_ CV* cv);
EXTERN_C void boot_DynaLoader (pTHXo_ CV* cv);

EXTERN_C void
xs_init(pTHXo)
{
    char *file = __FILE__;
    dXSUB_SYS;

    newXS("Sybase::OpnSrv::bootstrap", boot_Sybase__OpnSrv, file);
    /* DynaLoader is a special case */
    newXS("DynaLoader::boot_DynaLoader", boot_DynaLoader, file);
}
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which bootstraps all of the static modules when the perl interpreter is started.

Michael