If you're talking about simple variables, try this in your ~/.profile:

ONE=2233
TWO=3434
export ONE TWO
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And than use the following in your script:

my $value = "$ENV{ONE}/$ENV{TWO}";
print "my value is $value\n";
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Update: I figured, you wanted to get "2233/3434" as a result (as in a directory tree), but if you want what neuroball suggests below, please ignore my suggestion, as far as the quotes go ;)