while (<DATA>) {
    s/ (?=.*\s?-1 )/,/g;
    print;
}

__DATA__
01 fines name 2222 -P sws -1 reee.tee rrt
02 fi si 2232 -P sqww -1 re.wqw ttf
02 fi si-1 2232 -P sqww -1 re.wqw ttf

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This will replace spaces with commas before the last -1 in the file.

In reply to Re: perl substitue till found pattern in aline by rjt
in thread perl substitue till found pattern in aline by Vijay81

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