Windows? When I run Makefile.PL for DBD-ODBC-1.41 on Linux, I get the following: 
unixODBC 2.3.1
DRIVERS............: /etc/unixODBC/odbcinst.ini
SYSTEM DATA SOURCES: /etc/unixODBC/odbc.ini
FILE DATA SOURCES..: /etc/unixODBC/ODBCDataSources
USER DATA SOURCES..: /home/mb/.odbc.ini
SQLULEN Size.......: 8
SQLLEN Size........: 8
SQLSETPOSIROW Size.: 8

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All 64bit sizes.
dbdimp.h has this definition: 
    SQLLEN   RowCount;     /* Rows affected by insert, update, delete
             * (unreliable for SELECT)  */

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This member looks like it was the culprit here and somehow ended up as 32bit. The build output of DBD-ODBC should have some clues.

In reply to Re^3: Overflow of $DBI::rows by mbethke
in thread Overflow of $DBI::rows by DanEllison

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