Adding the key/value pairs one at a time, as shown by Kenosis, is the most obvious and straightforward way to do this. However, you could process all of your new data into separate key and value arrays using split and map before updating your %gene hash in one go via a slice.

$ perl -Mstrict -Mwarnings -MData::Dumper -e '
> my %gene = (
>    NCRNA00115 => 79854,
>    SAMD11     => 148398,
>    N0C2l      => 26155,
>    PLEKHN1    => 84069,
>    HES4       => 57801,
>    );
> print Data::Dumper->Dumpxs( [ \ %gene ], [ qw{ *gene } ] );
> 
> open my $newFH, q{<}, \ <<EOD or die qq{open: < HEREDOC: > $!\n};
> ATAD3B  83858
> ATAD3A  55210
> SSU72   29101
> SLC35E2 9906
> GNB1    2782
> TMEM52  339456
> EOD
> 
> my( @newKeys, @newValues );
> my $iter = 0;
> push @{ ++ $iter % 2 ? \ @newKeys : \ @newValues }, $_ for
>    map { split }
>    <$newFH>;
> 
> @gene{ @newKeys } = @newValues;
> print Data::Dumper->Dumpxs( [ \ %gene ], [ qw{ *gene } ] );'
%gene = (
          'HES4' => 57801,
          'N0C2l' => 26155,
          'PLEKHN1' => 84069,
          'NCRNA00115' => 79854,
          'SAMD11' => 148398
        );
%gene = (
          'HES4' => 57801,
          'TMEM52' => '339456',
          'SSU72' => '29101',
          'GNB1' => '2782',
          'PLEKHN1' => 84069,
          'NCRNA00115' => 79854,
          'ATAD3A' => '55210',
          'N0C2l' => 26155,
          'SLC35E2' => '9906',
          'ATAD3B' => '83858',
          'SAMD11' => 148398
        );
$

[download]

I hope this is of interest.

Cheers,

JohnGG

In reply to Re: pushing multiple key-value pairs into an existing hash by johngg
in thread pushing multiple key-value pairs into an existing hash by lomSpace

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