Better to meta-quote  $s2 to avoid strange effects from regex metacharacters in it ( //p regex modifier available with 5.10+):

>perl -wMstrict -le "my $s1 = 'foo not *UN*known but bar is'; my $s2 = '*UN*known'; ;; die qq{'$s2' not in '$s1'} unless $s1 =~ m{ \Q$s2\E }xmsp; print qq{all after: '${^POSTMATCH}'}; " all after: ' but bar is'

In reply to Re^2: Perl Substr by AnomalousMonk
in thread Perl Substr by lddzjwwy

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