First thing that pops into mind for me if you really want to avoid reading/re-writing entire file:

• Read in file until you find line near start you want to delete (note line number using $.
• Read in file in reverse until you find line near end to delete (can use File::ReadBackwards)
• Use Tie::File to represent file as an array
• Use splice to get rid of unwanted lines
• Then untie @array;

Disclaimer: I have limited experience with Tie::File, so not sure how it performs w/ larger files.

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