The perlperf manual page has some advice.
In my opinion, the most important part is profile first, so that you know where the slow parts are. Devel::NYTProf is the best profiler I've ever used, and I can highly recommend it.
If your application is backed by a database, it might also worth investigating if indexes might be missing. Most database servers the capability to log slow queries, which you should use and act upon.
In reply to Re: opcode caching / speed-up app
by moritz
in thread opcode caching / speed-up app
by rpike
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