I see this issues on strawberry perl 5.16.2.1 and Win32::API::CommPort 0.20 and Perl Tk both with a separate thread for comms and without it. Error manifests only on certain writes (not always) and solution described in the first post does fix the problem. This definitely requires a fix, as it costs days to debug... And probably is relevant to many people not being vocal...

In reply to Re^3: Really Odd Bug With LWP and Device::SerialPort by Anonymous Monk
in thread Really Odd Bug With LWP and Device::SerialPort by kschwab

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