I don't think it matters when reading from a file 

#!/usr/bin/perl --
use strict;
use warnings;
use Path::Tiny qw/ path /;
my $raw = "#!/usr/bin/perl --
use strict;
use warnings;
use Data::Dump qw/ dd /;
my \$line = q{};
while(<DATA>){
   \$line = \$_;
}
dd( \$line );
__DATA__
before sub
the \32
\32
" ;
$raw .= "after sub\n" x ( 1024 * 1024 );
$raw .= "out of buffer";
path( 'yada' )->spew_raw( $raw );


system $^X, 'yada';
path( 'yada' )->remove;

[download]

If memory serves Ctrl-Z only ever worked on STDIN, as in 

$ perl -
use Data::Dump qw/ dd /;
while(<DATA>){
  dd($_);
}
__DATA__
a
"a\n"
asdf^Z
"asdf\32\n"
^Z

[download]

In reply to Re^2: Perl stops reading __DATA__ when meeting SUB character on Windows (Ctrl-Z on STDIN) by Anonymous Monk
in thread Perl stops reading __DATA__ when meeting SUB character on Windows by yfnecz

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