Can you make a working code example, that dosn't use any OO program? That would identify wheter it's a Wx problem, or an improper object model which you use.

You could also check the reference type of $self to see what you are getting. 

sub Combobox1action {
    my( $self, $event ) = @_;

print $self, "\n";

    $self->SetTitle( 'Combo box selected' );
}

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If $self prints out to be a WxWidget Combobox, your code should work. But if $self turns out to be the package you are holding your code in, MyFrame, a WxWidget frame, then you will need to find a way of clearly identifying the Combobox.
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In reply to Re^3: Passing arguments to event handlers in WxPerl by zentara
in thread Passing arguments to event handlers in WxPerl by pwn01

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