I can't say anything regarding Perl on Win10 because I am still on Win7. I just want to add my 5 cents for the task of using different versions of any tools. I keep applications (as much as it is possible) in their own directories and create symlinks as below: 
mklink /d perl strawberry-perl-5.16.2.1-32bit

[download]
and the c:\full\path\to\perl\bin is specified in the %PATH% variable. When I need to switch to another Perl version I simply change the symlink 
rd perl
mklink /d perl strawberry-perl-5.8.8.3

[download]

In reply to Re: Perl on Windows 10 by siberia-man
in thread Perl on Windows 10 by kcott

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