See also the replies you got at Re^2: IO::Socket::SSL Connection Error and Re^2: IO::Socket::SSL Connection Error.

My recommendation is to check with curl instead of a browser. A good first step is to take the URL you have in your browser, and give it in a terminal to curl instead:

curl https://localhost:22222

[download]

In reply to Re: IO::Socket::SSL -> unexpected message ! by Corion
in thread IO::Socket::SSL -> unexpected message ! by Sascha2018

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