This seems to work: 

#!/usr/bin/perl
use strict;
use warnings;



my @header = qw/ chr fivep threep strand /;

my %output;

@ARGV = glob 'file*.tab';

while ( <> ) {
    tr/\t// == 8 or die "_ERROR_ not 9 columns: $_";

    my ( $key, $val ) = /^ ( [^\t]+ \t [^\t]+ \t [^\t]+ \t [^\t]+ ) \t
+ [^\t]+ \t [^\t]+ \t ( [^\t]+ ) /x;

    $output{ $key }[ @header - 4 ] = $val || 0;

    if ( eof ) {
        push @header, $ARGV;
        }
    }
        
print join( "\t", @header ), "\n";

for my $key ( keys %output ) {
    my $new = $key =~ s/ \t \K ( [^\t]+ ) \z / $1 eq '0' ? '+' : '-' /
+rex;

    $output{ $key }[ $_ ] //= 0 for 0 .. $#header - 4;

    print join( "\t", $new, @{ $output{ $key } } ), "\n";
    }

[download]

In reply to Re: open input files once by jwkrahn
in thread open input files once by v15

Title:
Use:  <p> text here (a paragraph) </p>
and:  <code> code here </code>
to format your post, it's "PerlMonks-approved HTML":


  • Posts are HTML formatted. Put <p> </p> tags around your paragraphs. Put <code> </code> tags around your code and data!
  • Titles consisting of a single word are discouraged, and in most cases are disallowed outright.
  • Read Where should I post X? if you're not absolutely sure you're posting in the right place.
  • Please read these before you post! —
  • Posts may use any of the Perl Monks Approved HTML tags:
    a, abbr, b, big, blockquote, br, caption, center, col, colgroup, dd, del, details, div, dl, dt, em, font, h1, h2, h3, h4, h5, h6, hr, i, ins, li, ol, p, pre, readmore, small, span, spoiler, strike, strong, sub, summary, sup, table, tbody, td, tfoot, th, thead, tr, tt, u, ul, wbr
  • You may need to use entities for some characters, as follows. (Exception: Within code tags, you can put the characters literally.)
            For:     Use:
    & &amp;
    < &lt;
    > &gt;
    [ &#91;
    ] &#93;
  • Link using PerlMonks shortcuts! What shortcuts can I use for linking?
  • See Writeup Formatting Tips and other pages linked from there for more info.