Setup a hash to keep a counter for each substituted token. Walk over the lines looking for a match. If it matches, replace with the token followed by the counter value (and increment the counter in your hash); otherwise copy the line.

Edit: tweaked updating counter hash. 

#!/usr/bin/env bb -i
;; https://github.com/babashka/babashka
(defn fix-line [ctrs l]
  (if-let [[_ pre to-fix] (re-matches #"(.*?\s+)(d?grs);" l)]
    (do
      (swap! ctrs update-in [to-fix] #(if % (inc %) 1))
      (format "%s%s_%d;" pre to-fix (get @ctrs to-fix)))
    l))

(let [ctrs (atom {})]
  (doseq [l *input*]
    (println (fix-line ctrs l))))

[download]
$ ./fwee.clj < terrible_sample.txt
wire  [130 : 0]         dgrs_1
wire  [130 : 0]         dgrs_2
wire  [130 : 0]         dgrs_3

wire  [130 : 0]         grs_1
wire  [130 : 0]         grs_2
wire  [130 : 0]         grs_3

[download]

The cake is a lie.
The cake is a lie.
The cake is a lie.

In reply to Re: To remove duplicate lines and add digits as per loop by Fletch
in thread To remove duplicate lines and add digits as per loop by suvendra123

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