Hi PerlMonks,

I am interested to randomize a DNA string in such a way that the number and the composition of elements in the DNA string remian the same but only the positions of elements are changed. For instance, I have a DNA string like "AATTGGCC" i.e. each base (A,T,G,C) has two copies. I want to get all possible combinations like ATATGGCC,AATGTGCC,ATATGCGC..etc. I am at a fix to find all the possible combinations from the string in perl. I looked for online resouces but I could not find the solution. I welcome suggestions from perlmonks. I have written a script which goes as follows. I have not written the code for combinations. 

#!/usr/bin/perl
use warnings;

 my $dna="aattggcc"; 
 $dna=uc$dna; 
print "\n dna: $dna\n";

# code for all possible combinations ? 

exit;

[download]

Results should look like:

 All possible combinations are:
 ATATGGCC
 AATGTGCC
 ATATGCGC
 ........

[download]

In reply to How can one randomize a DNA string without changing the composition? by supriyoch_2008

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