Yes! Except the above breaks, because the inner s/// kills the existing capture groups. So, those must be saved. E.g.

s{
  ( ^ \#[ ]START \n )
  ( .*?             )
  ( ^ \#[ ]END   \n )
}{
  my @m = @{^CAPTURE};
  $m[ 0 ] . ( $m[ 1 ] =~ s/^[ #]+//rmg ) . $m[ 2 ];
}xmesg;

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In reply to Re^2: s///g within m//g regions by almr
in thread s///g within m//g regions by almr

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