I did a small Perl script to parse your output, here are the results when processing the file: 

16384:
  total nb: 613635
  total time: 6885255
  avg time: 11.2204404898678
-1:
  total nb: 3779378
  total time: 10540192
  avg time: 2.78886949122316

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11.22 us in average for the "productive" calls of the SSL_read() function from libssl
2.79 us in average for the "unproductive" calls of the SSL_read() function from libssl

The "unproductive" calls timing at libssl side seems pretty consistent with the timing I have for the sysread calls in the non-SSL case (2.73 us).

In reply to Re^6: IO::Socket::SSL / Net::SSLeay inefficient in non-blocking mode ? by Yaribz
in thread IO::Socket::SSL / Net::SSLeay inefficient in non-blocking mode ? by Yaribz

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