I don't know about xquartz (as I said I don't own a Mac so I'm not familiar with what xquartz is), but you would have to install xorg from MacPorts like this:

sudo port install xorg
sudo port install p5-tk

that's taken from the macOS installation instructions for my application, these instructions were written for me by another macOS user (with an Intel Mac though).
http://obd-amigos.linuxtech.net/files/00-How_to_install_OBD_Amigos_on_macOS.html

Since these are MacPorts packages, isn't it quite easy to uninstall them cleanly again after the test, if you have no need for them?

Thanks for the one-liner test but unfortunately it's not as simple as that to trigger this issue, I also gave the user of my application a similar one-liner (but with eval) at first, without triggering the issue. I have a feeling that Tk is needed to trigger the issue.

In reply to Re^3: weird problem with macports perl on apple m1/m2 based system by perltux
in thread weird problem with macports perl on apple m1/m2 based system by perltux

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